The Blaze's Rachael Heyhoe Flint trophy tie against Sunrisers on Wednesday 13 September will now take place at the Haslegrave Ground.
The fixture was originally scheduled to be played at the John Fretwell Centre, home of Welbeck CC, but will now be staged on the Loughborough University campus with a 10.30am start.
The match is one of four remaining for The Blaze in the month of September, as Kirstie Gordon's side bid to qualify for 50-over finals day at Northampton.
The table-topping Blaze will face Central Sparks at Portland Road (5 September), before travelling to Beckenham to take on South East Stars (10 September).
The group stage concludes with two fixtures at Loughborough, with Sunrisers' visit being followed by a clash with Southern Vipers on Saturday 16 September.